Romanov family tree queen victoria pdf#

Describe how Alexis genetically acquired hemophilia.

The Romanov’s son, Alexis, had hemophilia.

The production of the VII and IX factors are either not produced correctly or not produced at all resulting in the process of clotting to fail.

How could the mutation you described in #12 result in a faulty gene product? Be very specific in your description.

More specifically a causal substitution in the splice acceptor site of exon 4 in the F9 gene.

The genes affected are the F8 and F9 genes that produce the corresponding VII and IX clotting factors needed to properly clot blood, The factors make a more permanent shell that would stop the flow of blood but without them blood flows freely.

Describe the mutation (at the molecular level) that apparently caused hemophilia in Alix, (and probably all of the European families that had hemophilia).

The Royal Family was plagued with Hemophilia B.

What type of hemophilia (A or B) is (probably) represented in the pedigree chart?.

As a result, the severity of Hemophilia depends on the number of available factors. People with Hemophilia have less than the normal number of Factors when compared to healthy people. Blood needs multiple clotting factors to properly clot.But WHY can’t the blood clot? Be very specific.) (Yes, I know it is severe bleeding because the blood cannot clot. In a couple of sentences, describe the physiology of the disease hemophilia.They only have the single X, so they cannot be a carrier because they either exhibit the symptoms or they do not.Why aren’t males considered carriers for hemophilia?.They do not exhibit the symptoms of the disease, but they can pass down the disease to descendants.

What does it mean to be a carrier for a disease?.The gene was found on the X chromosomes making females carriers or have the disease if they are homologous recessive, and males would have the disease since they can only have 1 Xīoth Queen Victoria and Alix are designated as being carriers for hemophilia.On what chromosome is the gene that, when mutated, causes hemophilia and how does this contribute to its inheritance pattern?.Alix was the granddaughter of Queen Victoria since her mother was Victoria’s daughter.How was Alix, the wife of Nicholas II, related to Queen Victoria of England? (Look at the pedigree chart carefully.).One of the pedigree charts found at the end of this assignment comes from the Module PowerPoint lecture notes. The white army was a group that was opposed to the Red Bolshevik army that removed the Tsar in the first place.just imprisoned) was because there was a fear that the White Russian Army would save them. One of the reasons that the family of Nicholas II was executed (vs.They were supposed to go into exile in England, but revolutionaries intercepted them and executed them.What happened to Nicholas II and his family after he abdicated the throne?.After he was abdicated the Monarchy was overthrown and a Revolutionary government was put in place.The crown stayed in power for about 304 years.How long had the Romanov family been in power in Russia?.

Nicholas II was the last Romanov to hold power in Russia.

Romanov family tree queen victoria pdf#

(Please note that this is a PDF of an article.) (You won’t be able to access the entire article, but the abstract will give you important information.) You may need to copy and paste the site address.) 838 (You should be able to access the entire article. You may use other Internet sources here, but please cite any sources that you use unless they are one of the following. Old Dominion University/BIOL294-Genetics/Rinehart-Kim/Romanov Project